Evaluating MicoRNA-21 of Human of Papillomavirus by RT-qPCR
Keywords:
MicoRNA-21, HPV, RT-qPCR, Breast CancerAbstract
Human samples from Breast Cancer patients were collected from October 2024 to December 2024.Breast Cancer was included (36 – 74 years). The RT-qPCR, Method was used to detect miR-21 of all samples. The population groups studied samples subject groups were distributed into 4 groups including (36-45,46-55,56-65, and 66-75,) years. The samples were isolated from the Hospital of the (Middle Euphrates Cancer Center) this is the first study in the region to explore the relationship between HPV infection and gene expression patterns, of microRNAin breast cancer patients. A significant reduction in the expression of miR-21-5p, was observed in HPV-positive cases, indicating a potential suppressive effect of HPV on key immunological and regulatory pathways within the tumor microenvironment.
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