Evaluation of Growth Indicators and Quality of Life in Children with Cleft Lip/Palate After Surgery
Keywords:
Cleft lip and palate (CLP), Oral health-related quality of life, Children, Adolescents, Surgery, Oral healthAbstract
Introduction: Oral clefts are a group of relatively common congenital anomalies, among which cleft lip and cleft palate (CLP) represent one of the major forms.
Methods: This study was conducted among patients with CLP. A total of 70 patients who had undergone CLP-related surgery were enrolled in the study. The study instrument consisted of several sections assessing demographic characteristics and Oral Health Impact Profile-14 (OHIP-14) questionnaire The collected data were then analyzed and compared using SPSS software, version 18.
Result: Based on the findings, 70 patients were enrolled in the study. Sixty percent of the participants were male, and the largest age group was 6–9 years (36.7%). Regarding parental education, 38.3% of fathers had a secondary education level, while 43.3% of mothers had completed primary education. The mean (SD) of the total OHIP-14 score before surgery was 45.60 (2.30). Post-operatively, this score significantly decreased to 30.21 (8.33), indicating a substantial improvement in the patients’ quality of life following the surgical procedure. Findings revealed a reduction in scores across all seven domains of the OHIP-14 questionnaire post-surgery, reflecting a significant enhancement in the patients’ OHRQoL. This improvement was statistically significant in all dimensions (P < 0.001).
Conclusion: Given the significant post-surgical improvement in OHRQoL, it is highly recommended that reconstructive surgeries and associated rehabilitative care be prioritized to optimize the quality of life for patients with CLPA.
References
Mossey PA, Little J, Munger RG, Dixon MJ, Shaw WC: Cleft lip and palate. Lancet 2009, 374(9703):1773-1785.
Pai BCJ, Hung YT, Wang RSH, Lo LJ: Outcome of Patients with Complete Unilateral Cleft Lip and Palate: 20-Year Follow-Up of a Treatment Protocol. Plast Reconstr Surg 2019, 143(2):359e-367e.
Farmer D, Sitkin N, Lofberg K, Donkor P, Ozgediz D: Essential surgery: disease control priorities. 2015.
Poenaru D: Getting the job done: analysis of the impact and effectiveness of the SmileTrain program in alleviating the global burden of cleft disease. World J Surg 2013, 37(7):1562-1570.
Singh SK: Smile Train: The ascendancy of cleft care in India. Indian J Plast Surg 2009, 42 Suppl(Suppl):S192-198.
Wydick B, Zahid M, Manning S, Maller J, Evsanaa K, Skjoldhorne S, Bloom M, Das A, Deshpande G: The Impact of Cleft Lip/Palate and Surgical Intervention on Adolescent Life Outcomes. Ann Glob Health 2022, 88(1):25.
Nelson PA, Kirk SA, Caress AL, Glenny AM: Parents' emotional and social experiences of caring for a child through cleft treatment. Qual Health Res 2012, 22(3):346-359.
Zeytinoglu S, Davey MP: It's a privilege to smile: impact of cleft lip palate on families. Fam Syst Health 2012, 30(3):265-277.
Berg E, Haaland ØA, Feragen KB, Filip C, Vindenes HA, Moster D, Lie RT, Sivertsen Å: Health Status Among Adults Born With an Oral Cleft in Norway. JAMA Pediatrics 2016, 170(11):1063-1070.
Meng T, Ma L, Wang Z: Comparative Assessment of the Cleft Profile by Patients with Cleft Lip and Palate, Cleft Surgeons, and Lay People. Aesthetic Plastic Surgery 2015, 39(5):757-763.
Reilly S, Reid J, Skeat J, Cahir P, Mei C, Bunik, the Academy of Breastfeeding Medicine M: ABM clinical protocol# 17: guidelines for breastfeeding infants with cleft lip, cleft palate, or cleft lip and palate, revised 2013. Breastfeeding Medicine 2013, 8(4):349-353.
Nyakotey D, Apprey C, Annan RA: Malnutrition in children with unrepaired orofacial cleft: a systematic review. 2019.
Ueki S, Fujita A, Kumagai Y, Hirai Y, Tashiro E, Miyata J: Bottle-feeding techniques for children with cleft lip and palate experiencing feeding difficulties. Int J Nurs Sci 2023, 10(1):82-88.
Kulkarni G, Rajput A, Kulkarni M, Pingale PL: Nutritional requirements of the pediatric and geriatric population. In: Nutrition and Women's Health. edn.: Elsevier; 2026: 123-139.
Thomassen RA, Kvammen JA, Bentsen BS, Solheim A, Størdal K, Henriksen C, Brun AC: Impact of parenteral nutrition on quality of life, the family and gastrointestinal symptoms in children with intestinal failure. Journal of Pediatric Gastroenterology and Nutrition 2025, 80(1):69-79.
Tabatabaeenia SH, Afshar EK, Kamyabi M: The effectiveness of Cognition-based Awareness on the Quality of Life and Mental Health of Women Undergoing Divorce in Referral to Judicial Centers1. A Journal of Police University and Women Police Traning Center 2023, 17(38).
Alotaibi M, Alobaysi S, Altammar M, Alaklabi S, Aladhyani M, Alruways O, Alobaysi O, Alruways A, Alotaibi A, Ali Y: Impact of early Adenotonsillectomy on Quality-of-Life improvement in Children with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.: eAT in quality of life of pediatric OSA. Saudi Medical Horizons Journal 2026, 6(1):50-59.
Piombino P, Ruggiero F, Dell’Aversana Orabona G, Scopelliti D, Bianchi A, De Simone F, Carnevale N, Brancati F, Iengo M, Grassia MG et al: Development and Validation of the Quality-of-Life Adolescent Cleft Questionnaire in Patients With Cleft Lip and Palate. Journal of Craniofacial Surgery 2014, 25(5):1757-1761.
Amran AJ, Rizqiawan A, Mulyawan I, Prasetio O, Subagio EW, Rahman MZ: Quality of life evaluation of Postsurgical mandibular fracture patients with oral health impact profile 14 and general oral health assessment index parameters. European Journal of Dentistry 2023, 17(04):1309-1315.
Warsi I, Younus A, Rasheed A, Ahmed J, Mahida H, Hashmi R, Qureshi A: Oral health-related quality of life in patients with upper gastrointestinal and hepatic disorders in Pakistan: validation of the Oral Health Impact Profile-14 in the Urdu language. BDJ Open 2018, 4:17036.
Pasini M, Cagidiaco I, Fambrini E, Miceli M, Carli E: Life Quality of Children Affected by Cleft Lip Palate and Alveolus (CLPA). Children 2022, 9(5):757.
de Oliveira Junior AG, Montagna E, Zaia V, Barbosa CP, Bianco B: Oral health-related quality of life in patients aged 8 to 19 years with cleft lip and palate: a systematic review and meta-analysis. BMC Oral Health 2023, 23(1):670.
Barros LAN, Jesuino FAS, de Paiva JB, Rino-Neto J, Valladares-Neto J: An oral health-related quality of life comparison between adults with unilateral cleft lip and palate and class III malocclusion. The Cleft Palate-Craniofacial Journal 2019, 56(10):1359-1365.
Corcoran M, Karki S, Harila V, Kyngäs H, Luoto A, Ylikontiola LP, Sándor GK, Anttonen V: Oral health‐related quality of life among young adults with cleft in northern Finland. Clinical and Experimental Dental Research 2020, 6(3):305-310.
de Lima Toyoshima GH, da Silva Costa SM, Costa MSC, Cota RME, de Oliveira TM, Soares S, Junior JFS, de Almeida ALPF: Fixed partial dentures in adult patients with cleft lip and palate and their relationship with the quality of life: A cross-sectional clinical study. The Journal of Prosthetic Dentistry 2024, 131(4):598-602.
Hashemi S, Derakhshandeh F, Dashti M, Abdali H: Oral health-related quality of life in adults with cleft lip and/or palate: A systematic review. Dental Research Journal 2026, 23(1):3.
